Case Studies: Real Failures & Wins
Instead of hype, critical thinking. Learn from partial data, make decisions, then reveal what actually happened.
Success Story
Insilico Medicine's Novel Inhibitor
First AI-designed drug to enter Phase II clinical trials
The Situation
Insilico used generative AI to design a novel small molecule for idiopathic pulmonary fibrosis.
Based on this information, would you continue this project?
Learning from Failure
The Selectivity Trap
High potency, wrong target engagement
The Situation
A computational campaign optimized for binding affinity achieved sub-nanomolar potency against the intended kinase.
Based on this information, would you continue this project?
Open Question
AlphaFold's Structural Revolution
Transformative tool with unclear drug discovery impact
The Situation
AlphaFold solved the protein structure prediction problem with remarkable accuracy.
Based on this information, would you continue this project?